Gen + lichaamsdeel Nieren en diabetes 56 ondersteunende bronnen vertrouwen 97% nieuwheid 62%

Het gen LHX1 wordt in 40 verhalen genoemd samen met nieren en de buisjes die urine afvoeren

We lazen 40 verhalen die het over zowel het gen LHX1 als over nieren en de buisjes die urine afvoeren hebben. Dat betekent niet zeker dat het één het ander veroorzaakt, maar het komt wel vaak samen voor.

Meer gen + lichaamsdeel

Hoe dit tot stand kwam

Dit gaat over wat er samen in de artikelen staat. Het is geen bewijs dat het ene het andere veroorzaakt.

Gegenereerd 2026-11-13, laatst gewijzigd vandaag. Dedup-sleutel assoc:LHX1:kidney. De engine controleert dit inzicht bij elke analyse opnieuw; als meer bronnen het eens zijn, stijgen zijn onderbouwing en vertrouwen en verschijnt het opnieuw als “nieuw”.

Bewijs (4 citaten)

Genetic Insights into Pediatric Polycystic Kidney Disease and Overlapping Ciliopathies: A Narrative Review peer-reviewed · gepubliceerd 2026-01-01 · live pagina

…30; Accepted 2026 Oct 8; Collection date 2026 Oct. 1. Introduction Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disorder and the leading genetic cause of chronic kidney disease (CKD) in adulthood. Based on comprehensive European registry and population sequenci…

The Importance of Molecular Testing in the Diagnosis of Genetic Syndromes with Chronic Kidney Disease: Genotype–Phenotype Correlations peer-reviewed · gepubliceerd 2026-01-01 · live pagina

…00 genes are associated with hereditary kidney disease, which may manifest as isolated kidney issues or as part of a syndrome that also includes extrarenal manifestations. The aim of this study was to identify genetic variants in a group of ten patients who presented with clinical signs suggestive of gen…

Hepatocyte nuclear factor 1 in renal lipid metabolism: molecular mechanisms and therapeutic potentials peer-reviewed · gepubliceerd 2025-01-01 · live pagina

…ng author. Contributed equally. Abstract Kidney disease is increasingly linked to dysregulated lipid metabolism, yet the molecular mechanisms driving renal lipotoxicity remain poorly understood. This review elucidates the pivotal role of the hepatic nuclear factor-1 family (HNF-1α and HNF-1β) in renal li…

Long-Read Sequencing in CKD Diagnostics: Breaking Genomic Barriers and Expanding Global Inclusion peer-reviewed · gepubliceerd 2026-01-01 · live pagina

…e of genetics in the assessment of CKD cases, stressing the need for thorough family history evaluations, consideration of the age of CKD onset, extrarenal symptoms, and the inclusion of genetic testing in the diagnostic process. 36 This review examines the current and emerging role of LRS in the diagnos…

Ondersteunende documenten (48)

Verhaal	Bron	Gepubliceerd	Gezien	Relevantie
17q12 Recurrent Deletion Syndrome in Childhood	pmc	2025-01-01	gisteren	1.00
Genetics of CAKUT	pmc	2026-01-01	gisteren	1.00
HNF1β, LHX1, and GGNBP2 deletion contributed to kidney and reproduc...	pmc	2024-01-01	gisteren	1.00
Prenatal diagnosis of 17q12 copy number variants in fetuses via chr...	pmc	2024-01-01	gisteren	1.00
HNF1B Transcription Factor: Key Regulator in Renal Physiology and P...	pmc	2024-01-01	gisteren	1.00
A Case of Diabetes Mellitus Type MODY5 as a Feature of 17q12 Deleti...	pmc	2024-01-01	gisteren	1.00
Recent advances in the molecular mechanisms of Mayer-Rokitansky-Küs...	pubmed	2017-08-01	gisteren	0.85
Copy number variation and regions of homozygosity analysis in patie...	pubmed	2018-01-01	gisteren	1.00
Autism and duplication of 17q12q21.2 by array-CGH: a case report.	pubmed	2023-01-01	gisteren	1.00
Monogenic Etiologies of Kidney Cysts in the Pediatric Population: A...	pubmed	2026-06-01	gisteren	1.00
HNF1B-MODY (MODY-5): a rare form of diabetes with multisystemic fea...	pubmed	2026-01-01	gisteren	1.00
In-Depth Phenotyping of PIGW -Related Disease and Its Role in 17q12...	pmc	2024-01-01	gisteren	1.00
The genetic etiologies of bilateral renal agenesis	pmc	2024-01-01	gisteren	1.00
Decreased T helper 1 cell function underlies recurrent sinopulmonar...	pmc	2025-01-01	gisteren	1.00
Case-based learning: a case of maturity-onset diabetes of the young...	pmc	2025-01-01	gisteren	1.00
Navigating Genetic Testing in Nephrology: Options and Decision-Maki...	pmc	2024-01-01	gisteren	1.00
Genetic Predisposition in Müllerian Malformations: A Case Report	pmc	2025-01-01	gisteren	1.00
Multi- and Transgenerational Histological and Transcriptomic Outcom...	pmc	2025-01-01	gisteren	0.97
Exome analysis links kidney malformations to developmental disorder...	pmc	2025-01-01	gisteren	1.00
Etiology and outcomes of fetal renal abnormalities in Southern Chin...	pmc	2025-01-01	gisteren	1.00
Cognitive deterioration in patients undergoing hemodialysis: how va...	pmc	2025-01-01	gisteren	1.00
Prenatal diagnosis of fetuses with renal abnormalities: a retrospec...	pmc	2025-01-01	gisteren	1.00
A Case of Amyotrophic Lateral Sclerosis With Coexisting Maturity-on...	pmc	2025-01-01	gisteren	1.00
MODY5 and 17q12 Microdeletion Syndrome: Phenotype Variability, Pren...	pmc	2025-01-01	gisteren	1.00
Building a human pluripotent stem cell-based gonadal niche: improvi...	pmc	2025-01-01	gisteren	0.97
Frame shift mutation of LHX1 is associated with Mayer-Rokitansky-Ku...	pubmed	2012-09-01	gisteren	1.00
TBX6, LHX1 and copy number variations in the complex genetics of Mü...	pubmed	2013-08-16	gisteren	1.00
The Genetic Landscape of Müllerian Duct Anomalies: A Comprehensive Review	pmc	2025-01-01	gisteren	1.00
Hepatocyte nuclear factor 1 in renal lipid metabolism: molecular me...	pmc	2025-01-01	gisteren	1.00
Clinical and genetic aspects of Mayer-Rokitansky-Küster-Hauser syndrome.	pubmed	2018-01-01	gisteren	1.00
ADVANCING GENETIC TESTING IN KIDNEY DISEASES: REPORT FROM A NATIONA...	pmc	2024-01-01	gisteren	1.00
From mutation to symptoms: a multi-center study on HNF1B -related n...	pmc	2025-01-01	gisteren	1.00
Maternal DNA methylation signatures of gestational diabetes across ...	pmc	2025-01-01	gisteren	0.76
Genetic Analysis of Prenatal Renal Abnormalities in 17q12 Microdele...	pmc	2025-01-01	gisteren	1.00
A complex microdeletion 17q12 phenotype in a patient with recurrent...	pubmed	2012-05-14	gisteren	1.00
Case Report: Nephrocalcinosis from pancreatic hypoplasia in HNF1B d...	pmc	2026-01-01	gisteren	1.00
Genetic and embryonic transcriptome analyses reveal the molecular a...	pmc	2025-01-01	gisteren	1.00
Unraveling the Genetic Mysteries of Müllerian Anomalies: Research A...	pmc	2026-01-01	gisteren	1.00
The Importance of Molecular Testing in the Diagnosis of Genetic Syn...	pmc	2026-01-01	gisteren	1.00
A novel inversion at 17q12 disrupting HNF1B gene in a patient with ...	pmc	2026-01-01	gisteren	1.00
Recurrent, Nonrecurrent, and De Novo Membranous Nephropathy After K...	pmc	2026-01-01	gisteren	1.00
Functional validation of a non-canonical HNF1B splice-site variant in MODY5	pmc	2026-01-01	gisteren	1.00
A familial case report of 17q12 recurrent deletion syndrome: clinic...	pmc	2026-01-01	gisteren	1.00
Long-Read Sequencing in CKD Diagnostics: Breaking Genomic Barriers ...	pmc	2026-01-01	gisteren	1.00
HNF1B -related disease: developmental origins, molecular mechanisms...	pmc	2026-01-01	gisteren	1.00
Clinical Spectrum and Early Renal Functional Variability in a Natio...	pmc	2026-01-01	gisteren	1.00
Precision Medicine in Pediatric Nephrology: From Shared Clinical Ph...	pmc	2026-01-01	gisteren	1.00
Genetic Insights into Pediatric Polycystic Kidney Disease and Overl...	pmc	2026-01-01	gisteren	1.00