17q12, explained for kidsdeletion syndrome · static snapshot
Adults Scientists Kids EN NL
Everything here was found on the internet and put together with help from a computer program that reads and writes (AI). It is here so you can learn — it is not the final word. Always check the real source. Read the whole notice
A new article Genes and families 1 supporting source confidence 97% novelty 75%

Thyroxine binding globulin deficiency due to a novel HNF1B gene variant in a young girl with high thyroxine requirement

Primary hypothyroidism is managed with oral levothyroxine (LT4) using a daily dose of 1.5 to 2 µg per kg. Elevated thyroid-stimulating hormone (TSH) despite a high dose of LT4 is a common problem and could be due to multiple etiologies, including poor drug compliance, thyroxine (T4) malabsorption, celiac disease, and consumptive hypothyroidism.

More a new article

How this was derived

Indexed from **openalex** on 2026-11-13 (relevance 1.00, tier peer_reviewed).

Generated 2026-11-13, last changed yesterday. Dedup key newdoc:514. The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.

Evidence (1 quote)

Thyroxine binding globulin deficiency due to a novel HNF1B gene variant in a young girl with high thyroxine requirement peer_reviewed · published 2026-09-03 · live page
Thyroxine binding globulin deficiency due to a novel HNF1B gene variant in a young girl with high thyroxine requirement Abstract Primary hypothyroidism is managed with oral levothyroxine (LT4) using a daily dose of 1.5 to 2 µg per kg.

Supporting documents (1)

StorySourcePublishedSeenRelevance
Thyroxine binding globulin deficiency due to a novel HNF1B gene var... openalex 2026-09-03 yesterday 1.00