Gene–trait link
Signs & symptoms
9 supporting sources
confidence 97%
novelty 53%
PIGW appears alongside liver and gallbladder in 9 sources
Across the collected corpus, the gene PIGW co-occurs with liver and gallbladder in 9 independent documents (of 18 documents mentioning PIGW and 109 mentioning liver and gallbladder). Association strength 0.08.
How this was derived
Co-occurrence is an *observation about the literature*, not proof of causation: it says these topics are discussed together in the sources we hold.
Generated 2026-11-13, last changed
yesterday. Dedup key assoc:PIGW:hepatic.
The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.
Evidence (4 quotes)
Application of array-comparative genomic hybridization in tetralogy of Fallot.
peer_reviewed
· published 2016-12-01
· live page
…ology, Professor of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, Saint Louis University Liver Center, 3635 Vista Avenue at Grand Boulevard, St. Louis, MO 63110-0250. E-mail: baconbr@slu.edu; fax: 314-577-8125 . Potential conflict of interest:…
HNF1B-MODY (MODY-5): a rare form of diabetes with multisystemic features–two case reports
peer_reviewed
· published 2026-01-01
· live page
…irst case, a 29-year-old woman, presented with diabetes, hypertension, bilateral renal cysts, mild chronic kidney disease (CKD), hypomagnesemia, mild liver enzyme elevations, and a complex Müllerian anomaly requiring surgical correction. She has maintained excellent metabolic control on metformin alone,…
Severe neonatal cholestasis in HNF1β deficiency: a case report and literature review
peer_reviewed
· published 2025-01-01
· live page
…lestasis was rapidly resolved with hormone therapy. Genetic analysis showed a de novo 17q chromosome deletion, including the HNF1β gene implicated in liver damage, and this was considered causative of the complex clinical phenotype. Our case highlights the relationship between congenital hypopituitarism…
Hepatocyte nuclear factor 1 in renal lipid metabolism: molecular mechanisms and therapeutic potentials
peer_reviewed
· published 2025-01-01
· live page
…hepatic transcriptional regulators but has since been recognized as master coordinators of metabolic homeostasis across multiple organs including the liver, kidneys, and pancreas(16-18). As a key hub in the regulation of systemic lipid homeostasis, HNF-1 family exerts biological functions by coordinating…