Gene–trait link
Signs & symptoms
104 supporting sources
confidence 97%
novelty 75%
HNF1B appears alongside genital and müllerian development in 64 sources
Across the collected corpus, the gene HNF1B co-occurs with genital and müllerian development in 64 independent documents (of 177 documents mentioning HNF1B and 121 mentioning genital and müllerian development). Association strength 0.36.
How this was derived
Co-occurrence is an *observation about the literature*, not proof of causation: it says these topics are discussed together in the sources we hold.
Generated 2026-11-13, last changed
today. Dedup key assoc:HNF1B:mullerian_gu.
The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.
Evidence (4 quotes)
The Genetic Landscape of Müllerian Duct Anomalies: A Comprehensive Review
peer_reviewed
· published 2025-01-01
· live page
…no. 3 (2015): 769-774.e2. 33. Philibert P., Biason‐Lauber A., Gueorguieva I., et al., "Molecular Analysis of WNT4 Gene in Four Adolescent Girls With Mullerian Duct Abnormality and Hyperandrogenism (Atypical Mayer‐Rokitansky‐Küster‐Hauser Syndrome)," Fertility and Sterility 95, no. 8 (2011): 2683-2686. 34. C…
Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance
peer_reviewed
· published 2026-01-01
· live page
ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that present with complex clinical features of which sev…
Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insights
peer_reviewed
· published 2025-01-01
· live page
…ML, Massin N, Martinerie L, Picard JY, Rey R, Lombès M et al. Lack of androgen receptor expression in Sertoli cells accounts for the absence of anti-Mullerian hormone repression during early human testis development. J Clin Endocrinol Metab 2009;94:1818-1825. Boulet AM, Capecchi MR. Signaling by FGF4 and FG…
Mayer–Rokitansky–Küster–Hauser syndrome with inguinal hernia, left renal fusion, and malrotation: a rare case
peer_reviewed
· published 2025-01-01
· live page
…ser (MRKH) syndrome refers to a syndrome of genital malformation with normal development of female external genitalia but abnormal development of the Müllerian duct, 1 characterized by congenital dysplasia of the uterus and upper part of the vagina (2/3), but normal development of secondary sexual characteri…