Phenotype expansion
kidney and urinary tract
1 supporting source
confidence 97%
novelty 90%
New observation reported: Although obesity and insulin resistance are not typical findings in HNF1A -MODY, emerging evidence suggests th…
A source describes a new or expanded observation: “Although obesity and insulin resistance are not typical findings in HNF1A -MODY, emerging evidence suggests that environmental and metabolic modifiers, such as maternal hyperglycemia during pregnancy or underlying metabolic syndrome, may influence disease expression [ 51 , 52 ].”
How this was derived
Flagged by novelty language (“for the first time”, “expands the phenotype”, …) in pmc.
Generated 2026-11-13, last changed
yesterday. Dedup key expansion:dde25a.
The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.
Evidence (1 quote)
Revealing Monogenic Diabetes: Clinical and Genetic Features of Pediatric MODY Cases in Türkiye: Single Center Experience
peer_reviewed
· published 2025-01-01
· live page
Although obesity and insulin resistance are not typical findings in HNF1A -MODY, emerging evidence suggests that environmental and metabolic modifiers, such as maternal hyperglycemia during pregnancy or underlying metabolic syndrome, may influence disease expression [ 51 , 52 ].
Supporting documents (1)
| Document | Source | Published | Seen | Relevance |
|---|---|---|---|---|
| Revealing Monogenic Diabetes: Clinical and Genetic Features of Pedi... | pmc | 2025-01-01 | yesterday | 1.00 |