Gene–trait link
Signs & symptoms
11 supporting sources
confidence 97%
novelty 53%
LHX1 appears alongside tumour risk in 11 sources
Across the collected corpus, the gene LHX1 co-occurs with tumour risk in 11 independent documents (of 66 documents mentioning LHX1 and 133 mentioning tumour risk). Association strength 0.08.
How this was derived
Co-occurrence is an *observation about the literature*, not proof of causation: it says these topics are discussed together in the sources we hold.
Generated 2026-11-14, last changed
today. Dedup key assoc:LHX1:cancer.
The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.
Evidence (4 quotes)
Cancer Cytogenetics: Deep Roots, New Branches in the Age of Omics
peer_reviewed
· published 2026-01-01
· live page
…some 22. Courtesy of Kristin Andersen, Oslo University Hospital-Radiumhospitalet. In addition to the Philadelphia chromosome, several other important tumor-associated chromosomal abnormalities were identified during the pre-banding period. In 1963, Lele, Penrose and Stallard reported a visible deletion o…
Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast.
peer_reviewed
· published 2015-03-01
· live page
…east. Lymphovascular invasion (LVI) and histologic grade are clinical parameters of high prognostic value in breast cancer and indicate the level of tumor aggressiveness. Many studies have focused on the association of breast cancer subtypes with gene expression and chromosomal profiles, but considerabl…
Comparative Copy Number Variation Profiling of GL01, an Immortalized Non-small Cell Lung Cancer Cell Line Derived from a Filipino Patient, and A549 Lung Adenocarcinoma Cells
peer_reviewed
· published 2025-01-01
· live page
…e derived is a 58-year-old female diagnosed with moderately differentiated primary lung adenocarcinoma. Immunohistochemistry of the patient's primary tumor showed positive staining for thyroid transcription factor 1 (TTF1) and Napsin A. Pleural effusion was collected from the patient at the Molecular Dia…
Germline–Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis
peer_reviewed
· published 2025-01-01
· live page
…sms by which inherited genetics facilitate cancer initiation might transit through its cooperation with specific somatic events that then dictate the tumor features. Through a germline-somatic tandem leading to steroid biosynthesis, we suggest a paradigm to study cancer initiation. Abstract The biologica…