Contradicting evidence
Research frontier
1 supporting source
confidence 97%
novelty 70%
Caution: Overall, 17q12-related HNF1B whole gene deletions were the predominant type in our HNF1B pathogenic variant sp…
A source reports no association or a negative finding: “Overall, 17q12-related HNF1B whole gene deletions were the predominant type in our HNF1B pathogenic variant spectrum, with no significant difference in the proportion of inherited versus de novo pathogenic variants ( p = 0.198).”
How this was derived
Kept visible so the knowledge base does not only show positive results.
Generated 2026-11-13, last changed
today. Dedup key negation:320b6a.
The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.
Evidence (1 quote)
From mutation to symptoms: a multi-center study on HNF1B -related nephropathy in Chinese children
peer_reviewed
· published 2025-01-01
· live page
Overall, 17q12-related HNF1B whole gene deletions were the predominant type in our HNF1B pathogenic variant spectrum, with no significant difference in the proportion of inherited versus de novo pathogenic variants ( p = 0.198).
Supporting documents (1)
| Article | Source | Published | Seen | Relevance |
|---|---|---|---|---|
| From mutation to symptoms: a multi-center study on HNF1B -related n... | pmc | 2025-01-01 | yesterday | 1.00 |