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New publication kidney and urinary tract 1 supporting source confidence 97% novelty 75%

Functional validation of a non-canonical HNF1B splice-site variant in MODY5

Functional validation of a non-canonical HNF1B splice-site variant in MODY5 Background Mutations in the HNF1B gene can cause developmental and functional abnormalities in multiple organs such as the pancreas, kidneys, and liver.

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How this was derived

Indexed from **openalex** on 2026-11-13 (relevance 1.00, tier peer_reviewed).

Generated 2026-11-13, last changed yesterday. Dedup key newdoc:554. The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.

Evidence (1 quote)

Functional validation of a non-canonical HNF1B splice-site variant in MODY5 peer_reviewed · published 2026-04-10 · live page
For patients with early-onset diabetes and extra-renal manifestations, if genetic screening for HNF1B exons and canonical splice sites yields negative results, the pathogenic potential of variants in introns and non-canonical splice sites should be carefully considered.

Supporting documents (1)

ArticleSourcePublishedSeenRelevance
Functional validation of a non-canonical HNF1B splice-site variant in MODY5 openalex 2026-04-10 yesterday 1.00