17q12 Knowledge Basedeletion syndrome · static snapshot
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Frequency / statistic kidney and urinary tract 1 supporting source confidence 97% novelty 60%

To visualize this complexity of assigning genetic causality in CAKUT, Martino et al. calculated incredible estimates of

A source reports “384 cases” in the context of kidney: “To visualize this complexity of assigning genetic causality in CAKUT, Martino et al. calculated incredible estimates of 93,384 cases and 9,244,968 controls needed to identify genome-wide significant associations in a theoretical but feasible scenario that incl”

How this was derived

Numbers are quoted verbatim from the source; check the source before quoting onward.

Generated 2026-11-13, last changed yesterday. Dedup key freq:384 cases. The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.

Evidence (1 quote)

To visualize this complexity of assigning genetic causality in CAKUT, Martino et al. calculated incredible estimates of 93,384 cases and 9,244,968 controls needed to identify genome-wide significant associations in a theoretical but feasible scenario that includes a disease prevalence of 1.0% (e.g., VUR or duplex kidney), effect size of OR = 1.5, and a minor allele frequency of 0.1% [ 37 ].

Supporting documents (1)

ArticleSourcePublishedSeenRelevance
Translational strategies to uncover the etiology of congenital anom... pmc 2024-01-01 yesterday 1.00