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A new article Genes and families 1 supporting source confidence 97% novelty 75%

Independent expansion, selection, and hypervariability of the TBC1D3 gene family in humans

TBC1D3 is a primate-specific gene family that has expanded in the human lineage and has been implicated in neuronal progenitor proliferation and expansion of the frontal cortex.

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How this was derived

Indexed from **pmc** on 2026-11-13 (relevance 1.00, tier peer_reviewed).

Generated 2026-11-13, last changed yesterday. Dedup key newdoc:389. The engine re-checks this insight on every analysis run; if more sources agree, its corroboration and confidence go up and it reappears as “new”.

Evidence (1 quote)

Independent expansion, selection, and hypervariability of the TBC1D3 gene family in humans peer_reviewed · published 2024-01-01 · live page
Instead, we propose that the human-specific modified C terminus plays a critical role in these adaptive functions by potentially directing novel post-translational modifications or altering the localization and trafficking of TBC1D3 proteins ( Sharma and Schiller 2019 ).

Supporting documents (1)

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Independent expansion, selection, and hypervariability of the TBC1D... pmc 2024-01-01 yesterday 1.00